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THE MACROPHAGE

被引：171
作者：
GORDON, S [1 ]
机构：
[1] UNIV OXFORD, SIR WILLIAM DUNN SCH PATHOL, S PARKS RD, OXFORD OX1 3RE, ENGLAND
来源：
BIOESSAYS | 1995年 / 17卷 / 11期
关键词：
D O I：
10.1002/bies.950171111
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied repertoire of plasma membrane and secretory molecules. Upon isolation from the body it continues to express special, as well as general, features of cellular organisation and function, which make it a delight to study in cell culture.
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页码：977 / 986
页数：10
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