CHANGE IN VARIANT TRANSTHYRETIN LEVELS IN PATIENTS WITH FAMILIAL AMYLOIDOTIC POLYNEUROPATHY TYPE-I FOLLOWING LIVER-TRANSPLANTATION

被引：67

作者：

ANDO, Y

TANAKA, Y

NAKAZATO, M

BOGORANERICZON

YAMASHITA, T

TASHIMA, K

SAKASHITA, N

SUGA, M

UCHINO, M

ANDO, M

机构：

[1] MIYAZAKI MED COLL,DEPT INTERNAL MED 3,MIYAZAKI 88916,JAPAN

[2] HUDDINGE HOSP,DEPT TRANSPLANTAT SURG,S-14186 HUDDINGE,SWEDEN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 211卷 / 02期

关键词：

D O I：

10.1006/bbrc.1995.1820

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three patients with familial amyloidotic polyneuropathy (FAP) type I underwent liver transplantation from heart-beating cadaveric donors. Since 2 patients underwent blood transfusion during the operation, variant transthyretin (TTR) levels in the plasma did not decrease time dependently. However, in 1 patient without blood transfusion variant TTR levels decreased in a time dependent manner and plasma half life of variant TTR was calculated to be 2.1 days. Total protein, normal, and variant TTR levels in cerebrospinal fluid (CSF) remained unchanged after liver transplantation. (C) 1995 Academic Press, Inc.

引用

页码：354 / 358

页数：5

共 13 条

[1] ROLE OF VARIANT PREALBUMIN IN THE PATHOGENESIS OF FAMILIAL AMYLOIDOTIC POLYNEUROPATHY - FATE OF NORMAL AND VARIANT PREALBUMIN IN THE CIRCULATION
ANDO, Y
IKEGAWA, S
MIYAZAKI, A
INOUE, M
MORINO, Y
ARAKI, S
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1989, 274 (01) : 87 - 93
[2] EFFECT OF LIVER-TRANSPLANTATION ON AUTONOMIC DYSFUNCTION IN FAMILIAL AMYLOIDOTIC POLYNEUROPATHY TYPE-I
ANDO, Y
TANAKA, Y
ANDO, E
YAMASHITA, T
NISHIDA, Y
TASHIMA, K
SUGA, M
UCHINO, M
ANDO, M
[J]. LANCET, 1995, 345 (8943): : 195 - 196
[3] TYPE-I FAMILIAL AMYLOIDOTIC POLYNEUROPATHY (JAPANESE TYPE)
ARAKI, S
[J]. BRAIN & DEVELOPMENT, 1984, 6 (02) : 128 - 133
[4] CAVALLARO T, 1990, INVEST OPHTH VIS SCI, V31, P7
[5] PROTEIN SIZE AND CEREBROSPINAL-FLUID COMPOSITION
FELGENHAUER, K
[J]. KLINISCHE WOCHENSCHRIFT, 1974, 52 (24): : 1158 - 1164
[6] LOWRY OH, 1951, J BIOL CHEM, V193, P265
[7] Mancini G, 1965, Immunochemistry, V2, P235, DOI 10.1016/0019-2791(65)90004-2
[8] NAKAZATO M, 1984, LANCET, V2, P1274
[9] DIAGNOSIS OF FAMILIAL AMYLOIDOTIC POLYNEUROPATHY BY RECOMBINANT DNA TECHNIQUES
SASAKI, H
SAKAKI, Y
MATSUO, H
GOTO, I
KUROIWA, Y
SAHASHI, I
TAKAHASHI, A
SHINODA, T
ISOBE, T
TAKAGI, Y
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 125 (02) : 636 - 642
[10] PREPARATION OF I131-LABELED HUMAN SERUM PREALBUMIN AND ITS METABOLISM IN NORMAL AND SICK PATIENTS
SOCOLOW, EL
WOEBER, KA
PURDY, RH
HOLLOWAY, MT
INGBAR, SH
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1965, 44 (10) : 1600 - &

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