MECHANISTIC STUDIES ON BETA-KETOACYL THIOLASE FROM ZOOGLOEA-RAMIGERA - IDENTIFICATION OF THE ACTIVE-SITE NUCLEOPHILE AS CYS89, ITS MUTATION TO SER89, AND KINETIC AND THERMODYNAMIC CHARACTERIZATION OF WILD-TYPE AND MUTANT ENZYMES

被引：93

作者：

THOMPSON, S

MAYERL, F

PEOPLES, OP

MASAMUNE, S

SINSKEY, AJ

WALSH, CT

机构：

[1] HARVARD UNIV,SCH MED,DEPT BIOL CHEM & MOLEC PHARMACOL,BOSTON,MA 02115

[2] MIT,DEPT BIOL,CAMBRIDGE,MA 02139

[3] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

BIOCHEMISTRY | 1989年 / 28卷 / 14期

关键词：

D O I：

10.1021/bi00440a006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：5735 / 5742

页数：8

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