PRETREATMENT OF URINE SAMPLES FOR THE ANALYSIS OF 11-NOR-DELTA-9-TETRAHYDROCANNABINOL-9-CARBOXYLIC ACID USING SOLID-PHASE EXTRACTION

被引：20

作者：

PARRY, RC

NOLAN, L

SHIREY, RE

WACHOB, GD

GISCH, DJ

机构：

[1] Supelco Inc., Bellefonte, PA, 16823, Supelco Park

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1990年 / 14卷 / 01期

关键词：

D O I：

10.1093/jat/14.1.39

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An extraction and concentration procedure using a unique solid-phase extraction tube was developed for the analysis of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine. Absolute and relative recoveries of the drug metabolite were found to be greater than 85% and 92%, respectively. The extraction procedure allows quantitation of the drug metabolite by GC/MS, HPLC with UV detection, or GC with flame ionization detection. The extraction procedure was verified with urine samples obtained from marijuana users as well as spiked urine samples. © 1990 Oxford University Press.

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页码：39 / 44

页数：6

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