EFFECTS OF VIRAL EXPOSURE OF THE 2-CELL MOUSE EMBRYO ON CLEAVAGE AND BLASTOCYST FORMATION INVITRO

被引：19

作者：

HEGGIE, AD ^{[1
]}

GADDIS, L ^{[1
]}

机构：

[1] RAINBOW BABIES & CHILDRENS HOSP,CLEVELAND,OH 44106

来源：

PEDIATRIC RESEARCH | 1979年 / 13卷 / 08期

关键词：

D O I：

10.1203/00006450-197908000-00013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The effect of viral exposure of two-cell mouse embryos on their capacity to undergo subsequent cleavage and blastocyst formation in vitro was determined. Exposure to Coxsackie viruses B-4 and B-6, reovirus type 2, influenza virus type A, mouse cytomegalovirus, adenovirus type 5, and mouse adenovirus resulted in statistically significant inhibition of blastocyst formation. Development in vitro was unaffected by exposure to ECHO virus type 11, attenuated poliomyelitis virus type 2, parainfluenza virus type 1, mumps, rubella, and herpes simplex viruses types 1 and 2. Blastocyst formation was also unaffected by exposure of embryos to mouse interferon in a concentration 24 units/ml of culture fluid. Coxsackie virus B-4 was recovered from exposed embryos. © 1979 International Pediatric Research Foundation, Inc.

引用

页码：937 / 941

页数：5

共 23 条

[1] INFECTION OF MAMMALIAN UNFERTILIZED AND FERTILIZED OVA WITH ONCOGENIC VIRUSES [J].