Measurements of the vertical ozone profile with balloon-borne sensors in the Arctic during January and February 1990 indicate repeated minima in the 22-km region. A general negative correlation of the 22-km ozone mixing ratio with time spent by the air parcel in regions cold enough for the formation of polar stratospheric clouds, together with the presence of sunlight on a portion of the air-parcel trajectory, and an inability to explain the ozone minimum by conventional dynamical processes, suggest that this feature is related to chemical ozone depletion.