ANTIMICROBIAL DITERPENES OF CROTON-SONDERIANUS .1. HARDWICKIC AND 3,4-SECOTRACHYLOBANOIC ACIDS

被引：46

作者：

MCCHESNEY, JD

CLARK, AM

SILVEIRA, ER

机构：

[1] UNIV FED CEARA, DEPT QUIM ORGAN & INORGAN, PROD NAT LAB, BR-60021 FORTALEZA, BRAZIL

[2] UNIV MISSISSIPPI, SCH PHARM, DEPT PHARMACOGNOSY, UNIVERSITY, MS 38677 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 06期

关键词：

D O I：

10.1021/np50078a021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The hexane-extracted resin of the roots of Croton sonderianus showed antimicrobial activity in standardized bioassays. Fractionation of the resin yielded two acidic diterpenes, (-)-hardwickic acid [2] and the new 3,4-secotrachylobanoic acid [5] as major bioactive materials.

引用

页码：1625 / 1633

页数：9

共 16 条

[1]

ANNONE A, 1979, ORG MAGN RESONANCE, V12, P429

[2]

Arigoni D, 1960, J CHEM SOC, P1900, DOI 10.1039/jr9600001900

[3] ANTI-MICROBIAL ACTIVITY OF PHENOLIC CONSTITUENTS OF MAGNOLIA-GRANDIFLORA L [J].