INFLUENCE OF N-PROPANOL ON GROWTH AND ANTIBIOTIC PRODUCTION BY AN INDUSTRIAL STRAIN OF STREPTOMYCES-ERYTHREUS UNDER DIFFERENT NUTRITIONAL CONDITIONS

被引：13

作者：

POTVIN, J ^{[1
]}

PERINGER, P ^{[1
]}

机构：

[1] ECOLE POLYTECH FED LAUSANNE,GENIE BIOL LAB,CH-1015 LAUSANNE,SWITZERLAND

来源：

BIOTECHNOLOGY LETTERS | 1993年 / 15卷 / 05期

关键词：

D O I：

10.1007/BF00129317

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The effect of propanol on primary and secondary metabolism of a glucose and phosphorus non-repressive strain of Streptomyces erythreus was studied. Propanol increased erythromycin final titer by 100% as well as biomass (20%), both occuring later in the course of the production phase. A growth-dissociated production metabolism is emphasized by propanol (higher beta value). A partly growth-associated production pathway tends to switch its production pattern (higher beta and lower alpha values) with propanol.

引用

页码：455 / 460

页数：6

共 10 条

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