SMI2 MEDIATED REDUCTIVE ADDITION OF BIS-PHENYLSULFONES TO KETONES

被引：23

作者：

CHANDRASEKHAR, S

YU, JR

FALCK, JR

MIOSKOWSKI, C

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT MOLEC GENET,DALLAS,TX 75235

[2] UNIV LOUIS PASTEUR STRASBOURG 1,FAC PHARM,CNRS,SYNTH BIOORGAN LAB,F-67401 ILLKIRCH GRAFFENS,FRANCE

[3] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 30期

关键词：

BETA-HYDROXYPHENYLSULFONE; DESULFONYLATION; ALKYLATION; DIIODOSAMARIUM;

D O I：

10.1016/S0040-4039(00)73520-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

SmI2 mediates the in situ reductive addition of geminal bis-phenylsulfones to unhindered ketones at room temperature affording beta-hydroxyphenylsulfones in good to excellent yields.

引用

页码：5441 / 5444

页数：4

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