DETERMINATION OF 5-FLUOROURACIL AND ITS MAIN METABOLITES BY ION-PAIR LIQUID-CHROMATOGRAPHY ON A MICROBORE COLUMN

被引：2

作者：

BARBERI, M ^{[1
]}

MERLIN, JL ^{[1
]}

WEBER, B ^{[1
]}

机构：

[1] CTR ALEXIS VAUTRIN,F-54511 VANDOEUVRE NANCY,FRANCE

来源：

NUCLEOSIDES & NUCLEOTIDES | 1990年 / 9卷 / 03期

关键词：

D O I：

10.1080/07328319008045162

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

5-Fluorouracil (5-Fu) and 5-Fluorodeoxyuidine (FdUrd) are substances widely used in the chemotherapy of cancers. The exploration of the metabolic pathways, is of great interest when they are combined with drugs which are likely to alter their biological response. The method described consists in the detection with ion-pair microbore HPLC of minimum amounts, ranging from 100 to 500 pg. © 1990, Taylor & Francis Group LLC. All rights reserved.

引用

页码：435 / 436

页数：2