CATALYTIC ENANTIOSELECTIVE SYNTHESIS OF (3S)-2,3-OXIDOSQUALENE

被引:24
作者
COREY, EJ
YI, KY
MATSUDA, SPT
机构
关键词
D O I
10.1016/S0040-4039(00)74200-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient and simple enantioselective process is described for the synthesis of (3S)-2,3-oxidosqualene (1) which provides this valuable compound contaminated with only 4% of the R enantiomer. The synthesis employs a chiral catalyst which is efficiently recovered for reuse.
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页码:2319 / 2322
页数:4
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