INHALATION OF PERTECHNEGAS - SIMILAR CLEARANCE FROM THE LUNGS TO THAT OF INHALED PERTECHNETATE AEROSOL

被引：12

作者：

ISAWA, T

TESHIMA, T

ANAZAWA, Y

MIKI, M

MAHMUD, AM

机构：

[1] Department of Respiratory Medicine, Institute of Development, Ageing and Cancer, Tohoku University, Aoba-ku Sendai, 980

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1995年 / 16卷 / 09期

关键词：

D O I：

10.1097/00006231-199509000-00004

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

It has been reported that the inhalation of pertechnegas (TGO(3)) generated under an atmosphere of 3% oxygen (O-2) in argon (Ar) instead of 100% Ar without O-2 in the technegas generator, offers a simple but accurate quantification of clearance from the lungs, permitting it to be used in place of Tc-99(m)-diethylenetriamine pentaacetic acid (DTPA). The disappearance from the lungs of inhaled TGO(3) was so similar to that of inhaled pertechnetate aerosol (TcO4) in this study, that there was neither a statistically significant difference in the clearance half-time (t(1/2)), nor a difference in the lung images between them. Neither TGO(3) nor TcO4 inhalation could distinguish smokers from non-smokers using t(1/2). When inhaled, TGO(3) appears to behave in a similar manner to TcO4 in the lungs and hence cannot be used in place of Tc-99(m)-DTPA in clinical practice.

引用

页码：741 / 746

页数：6

共 15 条

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