TOTAL SYNTHESIS OF (-)-TRANS-KUMAUSYNE

被引：40

作者：

OSUMI, K ^{[1
]}

SUGIMURA, H ^{[1
]}

机构：

[1] NOGUCHI INST,ITABASHI KU,TOKYO 173,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 32期

关键词：

D O I：

10.1016/00404-0399(50)1100V-

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (-)-trans-kumausyne has been accomplished in an enantiospecific fashion starting from an L-arabinose derivative. The key step is the stereoselective formation of the substituted tetrahydrofuran via novel cyclization of the beta-silyl cation intermediate, generated by the addition of allylsilane to di-O-isopropylidene-aldehydo-arabinose in the presence of boron trifluoride etherate.

引用

页码：5789 / 5792

页数：4

共 20 条

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