AGENT OF DISEASE CONTRACTED FROM GREEN MONKEYS

被引：80

作者：

KISSLING, RE

ROBINSON, RQ

MURPHY, FA

WHITFIELD, SG

机构：

[1] Virology Section, National Communicable Disease Center, Atlanta

来源：

SCIENCE | 1968年 / 160卷 / 3830期

关键词：

D O I：

10.1126/science.160.3830.888

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat.

引用

页码：888 / +

页数：1