RECONSTITUTION OF RESPIRATORY CONTROL OF SUCCINATE OXIDATION IN SUBMITOCHONDRIAL PARTICLES

被引:18
作者
LEE, CP
JOHANSSON, B
KING, TE
机构
[1] Johnson Research Foundation, University of Pennsylvania, Philadelphia
[2] Department of Chemistry, SUNY, Albany
关键词
D O I
10.1016/0006-291X(69)90274-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Reconstitution of respiratory control and the energy-dependent pyridine nucleotide transhydrogenation linked to succinate oxidation by soluble succinate dehydrogenase and the dehydrogenase-depleted particles is demonstrated. The restoration of succinate oxidation and respiratory control is a function of the concentration of succinate dehydrogenase present. Externally added succinate dehydrogenase effects neither the rate nor the respiratory control of NADH oxidation. The results are discussed in terms of the structural organization of the respiratory components in the mitochondrial membrane. © 1969.
引用
收藏
页码:243 / +
页数:1
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