LIFELONG CALCIUM INTAKE AND PREVENTION OF BONE FRAGILITY IN THE AGED

被引:19
作者
HEANEY, RP
机构
[1] Department of Health Sciences, Creighton University, Omaha, 68178, NE
关键词
BONE MASS; CALCIUM; ESTROGEN; PREVENTION; OSTEOPOROSIS;
D O I
10.1007/BF02555087
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary prevention of osteoporosis involves achieving the full genetic potential for bone mass. Secondary prevention is concerned with protecting what bone mass a woman may have at her current age. Calcium plays an important role in both. Calcium requirement varies with stage of growth, with physiological drains (e.g., pregnancy and lactation), and with factors that influence absorption and excretory loss (e.g., gonadal hormone status and sodium and protein intakes). The evidence is strong that prevailing calcium intakes contribute to the low bone mass component of osteoporotic fragility and that increases in intake would reduce the osteoporotic fracture burden. At the same time it needs to be emphasized that bone health is a multifactorial affair and that meeting calcium requirements alone will neither guarantee optimal bone growth nor protect against bone loss if other critical factors are missing. For example, calcium affords only minimal protection against either immobilization or estrogen withdrawal bone loss. Thus, while assuring an adequate calcium intake remains a sound strategy, it cannot be considered a total preventive for osteoporosis.
引用
收藏
页码:S42 / S45
页数:4
相关论文
共 34 条
[1]   CALCIUM INTAKE AND BONE HEALTH [J].
AVIOLI, LV ;
HEANEY, RP .
CALCIFIED TISSUE INTERNATIONAL, 1991, 48 (04) :221-223
[2]   DIETARY MODIFICATION WITH DAIRY-PRODUCTS FOR PREVENTING VERTEBRAL BONE LOSS IN PREMENOPAUSAL WOMEN - A 3-YEAR PROSPECTIVE-STUDY [J].
BARAN, D ;
SORENSEN, A ;
GRIMES, J ;
LEW, R ;
KARELLAS, A ;
JOHNSON, B ;
ROCHE, J .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (01) :264-270
[3]   PHYSICAL-ACTIVITY, MUSCLE STRENGTH, AND CALCIUM INTAKE IN FRACTURE OF THE PROXIMAL FEMUR IN BRITAIN [J].
COOPER, C ;
BARKER, DJP ;
WICKHAM, C .
BRITISH MEDICAL JOURNAL, 1988, 297 (6661) :1443-1446
[4]  
CUMMING RG, 1990, CALCIFIED TISSUE INT, V47, P194
[5]  
DAVIES K, 1989, J BONE MINER RES S1, V4, pS327
[6]   PALEOLITHIC NUTRITION - A CONSIDERATION OF ITS NATURE AND CURRENT IMPLICATIONS [J].
EATON, SB ;
KONNER, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (05) :283-289
[7]   POSTMENOPAUSAL BONE LOSS IS PREVENTED BY TREATMENT WITH LOW-DOSAGE ESTROGEN WITH CALCIUM [J].
ETTINGER, B ;
GENANT, HK ;
CANN, CE .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (01) :40-45
[8]  
Garn S. M., 1970, EARLIER GAIN LATER L
[9]  
Heaney R P, 1989, Public Health Rep, V104 Suppl, P36
[10]   OSTEOPOROTIC FRACTURE SPACE - AN HYPOTHESIS [J].
HEANEY, RP .
BONE AND MINERAL, 1989, 6 (01) :1-13