SANDOSTATIN AND THE BELFAST EXPERIENCE

被引：11

作者：

BUCHANAN, KD

COLLINS, JSA

VARGHESE, A

JOHNSTON, CF

SHAW, C

机构：

[1] Institute of Clinical Science, Queen’s University, Belfast

来源：

DIGESTION | 1990年 / 45卷

关键词：

Apudomas; Queen’s University of Belfast; Sandostatin;

D O I：

10.1159/000200255

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Twenty-four patients with 26 apudomas have been treated with Sandostatin (octreotide) in Belfast. The 2 patients with vipoma showed an excellent response clinically and biochemically. Of 15 patients with carcinoids, Sandostatin improved the diarrhoea in 70%. flush in 58%. and wheeze in 100% of patients. Patients with insulinoma and the Zollinger-Ellison syndrome were unresponsive to Sandostatin. In general, the response to Sandostatin appeared to decline as the tumour size increased and tumour markers rose. Side effects have not been a problem. © 1990 S. Karger AG, Basel.

引用

页码：11 / 16

页数：6

共 4 条

[1] NEUROENDOCRINE TUMORS - A EUROPEAN VIEW [J].

BUCHANAN, KD ;

JOHNSTON, CF ;

OHARE, MMT ;

ARDILL, JES ;

SHAW, C ;

COLLINS, JSA ;

WATSON, RGP ;

ATKINSON, AB ;

HADDEN, DR ;

KENNEDY, TL ;

SLOAN, JM .

AMERICAN JOURNAL OF MEDICINE, 1986, 81 (6B) :14-22

[2]

BUCHANAN KD, 1989, SCAND J GASTROENTERO, V21, P199

[3]

WATSON RGP, 1989, Q J MED, V72, P647

[4] LONG-TERM USE OF SOMATOSTATIN ANALOG SMS-201-995 IN THE TREATMENT OF HYPOGLYCEMIA DUE TO NESIDIOBLASTOSIS [J].

WILSON, DC ;

CARSON, DJ ;

QUINN, RJM .

ACTA PAEDIATRICA SCANDINAVICA, 1988, 77 (03) :467-470

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