SELECTION FOR SIGNAL SEQUENCE MUTATIONS THAT ENHANCE PRODUCTION OF SECRETED HUMAN PROINSULIN BY ESCHERICHIA-COLI

被引：7

作者：

STAHL, SJ

CHRISTIANSEN, L

机构：

[1] BIOGEN SA,DEPT MOLEC BIOL,CH-1211 GENEVA,SWITZERLAND

[2] NOVO RES INST,GENET LAB,DK-2880 BAGSVAERD,DENMARK

来源：

GENE | 1988年 / 71卷 / 01期

关键词：

D O I：

10.1016/0378-1119(88)90086-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：147 / 156

页数：10

共 31 条

[1]

BELL GI, 1980, NATURE, V284, P26, DOI 10.1038/284026a0

[2] TRANSFER OF PROTEINS ACROSS MEMBRANES .1. PRESENCE OF PROTEOLYTICALLY PROCESSED AND UNPROCESSED NASCENT IMMUNOGLOBULIN LIGHT-CHAINS ON MEMBRANE-BOUND RIBOSOMES OF MURINE MYELOMA [J].

BLOBEL, G ;

DOBBERSTEIN, B .

JOURNAL OF CELL BIOLOGY, 1975, 67 (03) :835-851

[3] CONSTRUCTION AND CHARACTERIZATION OF NEW CLONING VEHICLES .2. MULTIPURPOSE CLONING SYSTEM [J].

BOLIVAR, F ;

RODRIGUEZ, RL ;

GREENE, PJ ;

BETLACH, MC ;

HEYNEKER, HL ;

BOYER, HW ;

CROSA, JH ;

FALKOW, S .

GENE, 1977, 2 (02) :95-113

[4] A COMPLEMENTATION ANALYSIS OF RESTRICTION AND MODIFICATION OF DNA IN ESCHERICHIA COLI [J].

BOYER, HW ;

ROULLAND.D .

JOURNAL OF MOLECULAR BIOLOGY, 1969, 41 (03) :459-&

[5] A VECTOR FOR THE CONSTRUCTION OF TRANSLATIONAL FUSIONS TO TEM BETA-LACTAMASE AND THE ANALYSIS OF PROTEIN EXPORT SIGNALS AND MEMBRANE-PROTEIN TOPOLOGY [J].

BROOMESMITH, JK ;

SPRATT, BG .

GENE, 1986, 49 (03) :341-349

[6] BIOSYNTHESIS AND PERIPLASMIC SEGREGATION OF HUMAN PROINSULIN IN ESCHERICHIA-COLI [J].

CHAN, SJ ;

WEISS, J ;

KONRAD, M ;

WHITE, T ;

BAHL, C ;

YU, SD ;

MARKS, D ;

STEINER, DF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (09) :5401-5405

[7]

Davis RW, 1980, ADV BACTERIAL GENETI

[8]

DEBOER HA, 1983, P NATL ACAD SCI-BIOL, V80, P21

[9] IMPROVED METHODS FOR MAXIMIZING EXPRESSION OF A CLONED GENE - A BACTERIUM THAT SYNTHESIZES RABBIT BETA-GLOBIN [J].

GUARENTE, L ;

LAUER, G ;

ROBERTS, TM ;

PTASHNE, M .

CELL, 1980, 20 (02) :543-553

[10]

HEWICK RM, 1981, J BIOL CHEM, V256, P7990

← 1 2 3 4 →