ENANTIOSELECTIVE COMPLEXATION OF THE ALANINE DIPEPTIDE BY A C-2 HOST MOLECULE

被引：51

作者：

LIU, RP ^{[1
]}

SANDERSON, PEJ ^{[1
]}

STILL, WC ^{[1
]}

机构：

[1] COLUMBIA UNIV,DEPT CHEM,NEW YORK,NY 10027

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 18期

关键词：

D O I：

10.1021/jo00305a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: Starting from L-tyrosine, a chiral host molecule has been prepared which has an amide binding site and additional functionality which distinguishes guest chiral center substitutents based on steric and hydrogen bond donating properties. This molecule shows enantioselective binding (ΔΔ ~ 1 kcal/mol) of acetyl-L-alanineamides. © 1990, American Chemical Society. All rights reserved.

引用

页码：5184 / 5186

页数：3

共 7 条

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