SELECTIVE NEUROTOXIC ACTION OF CAPSAICIN ON GLOMERULAR C-TYPE TERMINALS IN RAT SUBSTANTIA GELATINOSA

被引：47

作者：

PALERMO, NN

BROWN, HK

SMITH, DL

机构：

[1] UNIV S FLORIDA, COLL MED, DEPT PHARMACOL & THERAPEUT, TAMPA, FL 33612 USA

[2] UNIV S FLORIDA, COLL MED, DEPT ANAT, TAMPA, FL 33612 USA

来源：

BRAIN RESEARCH | 1981年 / 208卷 / 02期

关键词：

D O I：

10.1016/0006-8993(81)90585-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Capsaicin exerts a selective neurotoxic action to induce degeneration of glomerular C-type nerve terminals in adult rats. Since the C terminals may be essential components of the circuitry for modulation of pain, it is suggested that capsaicin induced analgesia is the result of this neurotoxic action.

引用

页码：506 / 510

页数：5

共 18 条

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