DIACETYLENIC LIPID TUBULES - EXPERIMENTAL-EVIDENCE FOR A CHIRAL MOLECULAR ARCHITECTURE

被引：172

作者：

SCHNUR, JM ^{[1
]}

RATNA, BR ^{[1
]}

SELINGER, JV ^{[1
]}

SINGH, A ^{[1
]}

JYOTHI, G ^{[1
]}

EASWARAN, KRK ^{[1
]}

机构：

[1] INDIAN INST SCI,MOLEC BIOPHYS UNIT,BANGALORE 560012,KARNATAKA,INDIA

来源：

SCIENCE | 1994年 / 264卷 / 5161期

关键词：

D O I：

10.1126/science.264.5161.945

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Molecular self-assembly is of key importance for the rational design of advanced materials. To investigate the causal relation between molecular structure and the consequent self-assembled microstructure, self-assembled tubules of diacetylenic lipids were studied. Circular-dichroism studies give experimental evidence that the formation of tubules is driven by chiral molecular packing, in agreement with recent theories of tubules. On the basis of these results, a molecular mechanism for the formation of tubules is proposed.

引用

页码：945 / 947

页数：3

共 27 条

[1] A MODEL FOR CRYSTALLINE ORDER WITHIN HELICAL AND TUBULAR STRUCTURES OF CHIRAL BILAYERS [J].

CHAPPELL, JS ;

YAGER, P .

CHEMISTRY AND PHYSICS OF LIPIDS, 1991, 58 (03) :253-258

[2] ELASTIC FREE-ENERGY OF ANISOTROPIC HELICAL RIBBONS AS METASTABLE INTERMEDIATES IN THE CRYSTALLIZATION OF CHOLESTEROL [J].

CHUNG, DS ;

BENEDEK, GB ;

KONIKOFF, FM ;

DONOVAN, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (23) :11341-11345

[3]

DEGENNES PG, 1993, PHYSICS LIQUID CRYST

[4] HELICAL AND TUBULAR MICROSTRUCTURES FORMED BY POLYMERIZABLE PHOSPHATIDYLCHOLINES [J].

GEORGER, JH ;

SINGH, A ;

PRICE, RR ;

SCHNUR, JM ;

YAGER, P ;

SCHOEN, PE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (20) :6169-6175

[5]

Goodby JW., 1991, FERROELECTRIC LIQUID, V7

[6] INTRINSIC BENDING FORCE IN ANISOTROPIC MEMBRANES MADE OF CHIRAL MOLECULES [J].

HELFRICH, W ;

PROST, J .

PHYSICAL REVIEW A, 1988, 38 (06) :3065-3068

[7] THEORY OF RIPPLE PHASES OF LIPID BILAYERS [J].

LUBENSKY, TC ;

MACKINTOSH, FC .

PHYSICAL REVIEW LETTERS, 1993, 71 (10) :1565-1568

[8] SELF-ASSEMBLING PROPERTIES OF 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOHYDROXYETHANOL - A HEADGROUP-MODIFIED DIACETYLENIC PHOSPHOLIPID [J].

MARKOWITZ, M ;

SINGH, A .

LANGMUIR, 1991, 7 (01) :16-18

[9] OPTICAL MICROSCOPIC STUDY OF HELICAL SUPERSTRUCTURES OF CHIRAL BILAYER-MEMBRANES [J].

NAKASHIMA, N ;

ASAKUMA, S ;

KUNITAKE, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (02) :509-510

[10]

NAKASHIMA R, 1994, LANGMUIR, V10, P232

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