EFFECT OF INSULIN ON GLUCAGON ENHANCED LIPOLYSIS IN VITRO

被引:32
作者
LEFEBVRE, PJ
LUYCKX, AS
机构
[1] Institut de Médecine, Département de Clinique et de Pathologie Médicales, Secteur Diabétologie, Université de Liège
关键词
adipose tissue; FFA; glucagon; Insulin; lipolysis;
D O I
10.1007/BF01213680
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Glucagon in concentrations similar to those found in human plasma markedly stimulates lipolysis in rat adipose tissue in vitro. The effects of these physiological" concentrations of glucagon are reduced or abolished by insulin at concentrations of 25 and 100 μU/ml. Considering the marked insulinogenic effect of glucagon these observations may provide an explanation for the delayed increase of blood FFA observed after glucagon injection in vivo. © 1969 Springer-Verlag."
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页码:195 / &
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