THE STEREOSELECTIVE ALKYLATION AND CONFORMATIONAL-ANALYSIS OF 15-HEXADECANOLIDE

被引：9

作者：

GRAHAM, RJ ^{[1
]}

WEILER, L ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1Y6,BC,CANADA

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 08期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(00)74478-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

15-Hexadecanolide can be alkylated with 80% stereoselectivity. The stereochemistry of the major product was proven by chemical correlation with the alkylation products of cyclopentadecanone. A simple model using the [4444] conformation of cyclohexadecane is proposed to rationalize these results along with molecular mechanics calculations.

引用

页码：1027 / 1030

页数：4

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