GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC CHEMICAL IONIZATION ASSAY FOR HALOPERIDOL WITH SELECTED ION MONITORING

被引：16

作者：

HORNBECK, CL

GRIFFITHS, JC

NEBORSKY, RJ

FAULKNER, MA

机构：

[1] VET ADM HOSP,MED CTR,DEPT LAB SERV,PHARMACOKINET LAB,SAN DIEGO,CA 92161

[2] UNIV CALIF SAN DIEGO,SCH MED,DEPT PSYCHIAT,LA JOLLA,CA 92093

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 10期

关键词：

D O I：

10.1002/bms.1200061004

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A new gas chromatographic mass spectrometric chemical ionization assay for haloperidol with selected ion monitoring is presented which provides for better combined selectivity and sensitivity than previous asays. Levels of haloperidol in 2 ml of human plasma were reproducibly measured down to subnanogram levels. Both methane and methane‐ammonia chemical ionization spectra are presented for haloperidol and the internal standard trifluperidol. Copyright © 1979 Heyden & Son Ltd

引用

页码：427 / 430

页数：4

共 12 条

[1] RAPID AND SENSITIVE METHOD FOR DETERMINATION OF HALOPERIDOL IN HUMAN SAMPLES USING NITROGEN-PHOSPHORUS SELECTIVE DETECTION [J].