CUTANEOUS ANAPLASTIC T-CELL LYMPHOMA IN A PATIENT WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - DETECTION OF EPSTEIN-BARR-VIRUS DNA

被引：22

作者：

DRENO, B ^{[1
]}

MILPIEDHOMSI, B ^{[1
]}

MOREAU, P ^{[1
]}

BUREAU, B ^{[1
]}

LITOUX, P ^{[1
]}

机构：

[1] HOSP LORIENT,DEPT MED,F-56100 LORIENT,FRANCE

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1993年 / 129卷 / 01期

关键词：

D O I：

10.1111/j.1365-2133.1993.tb03316.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The Epstein-Barr virus (EBV) genome exists in tumour cells of T-cell lymphomas in non-immunosuppressed patients. We identified EBV-DNA by in situ hybridization in a case of anaplastic T-cell lymphoma associated with acquired immunodeficiency syndrome (AIDS). EBV-DNA has been reported in AIDS-related Hodgkin's disease or B-cell lymphoma, but never in T-cell lymphoma. Although our results suggest that EBV could play a role in the development of these anaplastic T-cell lymphomas, the mechanism of EBV penetration into T-cells remains uncertain.

引用

页码：77 / 81

页数：5

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