ROLE OF PROLACTIN IN THE EXPRESSION OF CASEIN GENES IN THE VIRGIN RABBIT

被引:19
作者
HOUDEBINE, LM
机构
[1] Laboratoire de Physiologie de la Lactation, Institut national de la Recherche Agronomique, C.N.R.Z.
来源
CELL DIFFERENTIATION | 1979年 / 8卷 / 01期
关键词
D O I
10.1016/0045-6039(79)90017-4
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Prolactin was injected into mature virgin rabbits. Casein mRNA, already present prior to the treatment was enhanced by prolactin. This accumulation of casein mRNA was not accompanied by a parallel significant synthesis of casein. The effect of prolactin took place without a previous cellular multiplication. The mammary cell is therefore sensitive to prolactin before the first pregnancy but prolactin then displays only an abortive effect on the expression of casein genes. © 1979.
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页码:49 / 59
页数:11
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