THE 2-STAGE MECHANISM CONTROLLING CELLULAR SENESCENCE AND IMMORTALIZATION

被引：313

作者：

WRIGHT, WE

SHAY, JW

机构：

[1] University of Texas Southwestern Medical Center, Dallas, TX 75235-9039

来源：

EXPERIMENTAL GERONTOLOGY | 1992年 / 27卷 / 04期

关键词：

AGING; SENESCENCE; RETINOBLASTOMA GENE PRODUCT; P53; TELOMERES; LIFE SPAN;

D O I：

10.1016/0531-5565(92)90069-C

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

[No abstract available]

引用

页码：383 / 389

页数：7

共 15 条

[1] POSITION EFFECT AT SACCHAROMYCES-CEREVISIAE TELOMERES - REVERSIBLE REPRESSION OF POL-II TRANSCRIPTION
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[2] COOPERATIVE EFFECT OF ANTISENSE-RB AND ANTISENSE-P53 OLIGOMERS ON THE EXTENSION OF LIFE-SPAN IN HUMAN-DIPLOID FIBROBLASTS, TIG-1
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TSURUI, H
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[3] TELOMERES SHORTEN DURING AGING OF HUMAN FIBROBLASTS
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[4] PROGRESS OF AGING IN HUMAN-DIPLOID CELLS TRANSFORMED WITH A TSA MUTANT OF SIMIAN VIRUS-40
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[5] TRANSFORMATION OF HUMAN CELLS BY TEMPERATURE-SENSITIVE MUTANTS OF SIMIAN VIRUS-40
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[J]. INTERVIROLOGY, 1978, 9 (01) : 28 - 38
[6] THEORY OF MARGINOTOMY - INCOMPLETE COPYING OF TEMPLATE MARGIN IN ENZYMIC-SYNTHESIS OF POLYNUCLEOTIDES AND BIOLOGICAL SIGNIFICANCE OF PHENOMENON
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[J]. JOURNAL OF THEORETICAL BIOLOGY, 1973, 41 (01) : 181 - 190
[7] FUNCTIONAL SIMIAN VIRUS-40T ANTIGEN IS EXPRESSED IN HYBRID-CELLS HAVING FINITE PROLIFERATIVE POTENTIAL
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[J]. MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (04) : 1541 - 1544
[8] EVIDENCE FOR THE RECESSIVE NATURE OF CELLULAR IMMORTALITY
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[J]. SCIENCE, 1983, 221 (4614) : 964 - 966
[9] DEFINING THE MOLECULAR MECHANISMS OF HUMAN CELL IMMORTALIZATION
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[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1072 (01) : 1 - 7
[10] A ROLE FOR BOTH RB AND P53 IN THE REGULATION OF HUMAN CELLULAR SENESCENCE
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[J]. EXPERIMENTAL CELL RESEARCH, 1991, 196 (01) : 33 - 39

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