CONCENTRATION OF ALPHA-1-ANTITRYPSIN IN CEREBROSPINAL-FLUID AND SERUM IN A SERIES OF 40 INTRACRANIAL TUMORS

被引：15

作者：

GALVEZ, S ^{[1
]}

FARCAS, A ^{[1
]}

MONARI, M ^{[1
]}

机构：

[1] INST NEUROCIRUGIA INVEST CEREBR ALFONSO ASENJO, DEPT BIOCHEM, SANTIAGO, CHILE

来源：

CLINICA CHIMICA ACTA | 1979年 / 91卷 / 02期

关键词：

D O I：

10.1016/0009-8981(79)90456-X

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Forty patients with histologically proved intracranial tumors were submitted to preoperative lumbar and venous punctures. The concentration of alpha-1-antitrypsin in the serum and in cerebrospinal fluid was determined by radial immunodiffusion technique. In the series, both serum and cerebrospinal fluid alpha-1-antitrypsin concentrations are significantly higher than the mean normal values. No statistical differences are observed in serum alpha-1-antitrypsin levels between benign and malignant tumors, but cerebrospinal fluid alpha-1-antitrypsin is significantly increased in the group of malignant tumors if cases undergoing steroid treatment are excluded. The diagnostic value of alpha-1-antitrypsin determinations in groups of patients with intracranial tumors is suggested. © 1979.

引用

页码：191 / 196

页数：6

共 10 条

[1] ERIKSSON S, 1974, ACTA MED SCAND, V195, P451
[2] GALVEZ S, 1976, NEUROCIRUGIA CHILE, V3, P13
[3] HARRIS CC, 1974, CANCER-AM CANCER SOC, V34, P280, DOI 10.1002/1097-0142(197408)34:2<280::AID-CNCR2820340210>3.0.CO
[4] 2-4
[5] LIEBERMAN J, 1975, AM J CLIN PATHOL, V64, P304
[6] EMPHYSEMA, CIRRHOSIS, AND HEPATOMA WITH ALPHA-1 ANTITRYPSIN DEFICIENCY
LIEBERMAN, J
[J]. ANNALS OF INTERNAL MEDICINE, 1974, 81 (06) : 850 - 852
[7] LOWRY OH, 1951, J BIOL CHEM, V193, P265
[8] Mancini G, 1965, Immunochemistry, V2, P235, DOI 10.1016/0019-2791(65)90004-2
[9] HEPATOCELLULAR CARCINOMA AND PARTIAL DEFICIENCY OF ALPHA-1 ANTITRYPSIN (MZ)
RAWLINGS, W
MOSS, J
COOPER, HS
HAMILTON, SR
[J]. ANNALS OF INTERNAL MEDICINE, 1974, 81 (06) : 771 - 773
[10] Spiegel M R., 1963, THEORY PROBLEMS ADV

← 1 →