STRUCTURE OF PERMETIN-A, A NEW POLYPEPTIN TYPE ANTIBIOTIC PRODUCED BY BACILLUS-CIRCULANS

被引：26

作者：

TAKEUCHI, Y

MURAI, A

TAKAHARA, Y

KAINOSHO, M

机构：

[1] Central Research Laboratories, Ajinomoto Co., Inc., Kawasaki, 210, 1-1 Suzuki-cho, Kawasaki-ku

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 02期

关键词：

D O I：

10.7164/antibiotics.32.121

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structure of permetin A(I), an antibiotic substance produced by Bacillus circulans AJ 3902, has been elucidated as a cyclic acyl peptide by means of the mass and nuclear magnetic resonance spectroscopic techniques. [formula ommited] The structure was found to be the same as polypeptin A(II) except that L-Thr in II is replaced by L-Ser in I. Details of the structural determination are given for the permetin A itself as well as for the hydrolyzed permetin A. [formula ommited]. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：121 / 129

页数：9

共 8 条

[1]

HALPERN B, 1966, TETRAHEDRON LETT, P2283

[2] RESOLUTION OF RACEMIC AMINO-ACIDS BY GAS-CHROMATOGRAPHY .1. N-TRIFLUOROACETYL-L-PROLYL DERIVATIVES [J].