WEINBERSTEROL DISULFATE-A AND DISULFATE-B, ANTIVIRAL STEROID SULFATES FROM THE SPONGE PETROSIA-WEINBERGI

被引：50

作者：

SUN, HH

CROSS, SS

GUNASEKERA, M

KOEHN, FE

机构：

[1] Division of Biomedical Marine Research Harbor Branch Oceanographic Institution, Inc., Fort Pierce, FL 34946

来源：

TETRAHEDRON | 1991年 / 47卷 / 07期

关键词：

D O I：

10.1016/S0040-4020(01)86375-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Weinbersterol disulfates A (1) and B (2), two new sulfated tetrahydroxy steroids with an unprecedented cyclopropane-containing side chain, were isolated from the sponge Petrosia weinbergi. Both compounds are active in vitro against feline leukemia virus, and 1 is also active in vitro against HIV. The structures of these two compounds were assigned mainly on the basis of spectral data.

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页码：1185 / 1190

页数：6

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