A REGULATORY MUTATION IN TYROSINE BIOSYNTHESIS

被引：18

作者：

GOLLUB, E

SPRINSON, DB

机构：

[1] Department of Biochemistry, College of Physicians and Surgeons, Columbia University, New York

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 35卷 / 03期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-291X(69)90511-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mutants of Salmonella with an altered control of the tyrosine repressible enzymes were obtained by selection for resistance to 4-fluoro-phenylalanine. The tyrosine repressible 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase and prephenate dehydrogenase (specified by aroF, and tyr, respectively) were constitutively and co-ordinately derepressed. The mutation to resistance was co-transducible with aroF and tyr. A unit of regulation in tyrosine biosynthesis in indicated. © 1969.

引用

页码：389 / &

共 14 条

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