STRUCTURE OF ASUKAMYCIN, A POSSIBLE SHUNT METABOLITE FROM 3-DEHYDROQUINIC ACID IN THE SHIKIMATE PATHWAY

被引：88

作者：

KAKINUMA, K ^{[1
]}

IKEKAWA, N ^{[1
]}

NAKAGAWA, A ^{[1
]}

OMURA, S ^{[1
]}

机构：

[1] KITASATO UNIV,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1979年 / 101卷 / 12期

关键词：

D O I：

10.1021/ja00506a056

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asukamycin (1) is an antibiotic, produced by Streptomyces nodosus subsp. asukaensis, showing antimicrobial activity against Gram-positive bacteria as well as anticoccidial activity in chikens,1 We here assign the structure of 1, which is proved to have a naturally unique monosubstituted cyclohexane structure. Furthermore, the stereochemical features of 1 are also described since the stereochemistry of a related antibiotic manumycin (2),2 elaborated by Streptomyces parvus, has not been reported. © 1979, American Chemical Society. All rights reserved.

引用

页码：3402 / 3404

页数：3

共 7 条

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[6]

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[7]

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