NOCTURNAL GROWTH-HORMONE SECRETION IN SCHIZOPHRENIC-PATIENTS AND HEALTHY-SUBJECTS

被引：13

作者：

KAHN, RS

DAVIDSON, M

HIRSCHOWITZ, J

STERN, RG

DAVIS, BM

GABRIEL, S

MOORE, C

DAVIS, KL

机构：

[1] BRONX VET ADM MED CTR,SERV PSYCHIAT,BRONX,NY 10468

[2] CUNY MT SINAI SCH MED,NEUROENDOCRINOL LAB,NEW YORK,NY 10029

来源：

PSYCHIATRY RESEARCH | 1992年 / 41卷 / 02期

关键词：

PSYCHOENDOCRINOLOGY; HORMONES; DOPAMINE; SEROTONIN;

D O I：

10.1016/0165-1781(92)90107-E

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

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收藏

页码：155 / 161

页数：7

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