Synthesis of 6 alpha, 7 beta-di-hydroxyvouacapan-17 beta-oic acid Derivatives. Parte I: Hydroxamic Acid and Amide Derivatives

被引：29

作者：

Rubinger, Mayura M. M. ^{[1
]}

Veloso, Dorila Pilo ^{[1
]}

Stefani, Guglielmo Marconi ^{[1
]}

Alves, Dalton L. Ferreira ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, ICEx, Dept Quim, BR-31270 Belo Horizonte, MG, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 1991年 / 2卷 / 03期

关键词：

6; alpha; 7 beta-di-hydroxyvouacapan-17 beta-oic acid; anti-inflammatory;

D O I：

10.5935/0103-5053.19910027

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

6 alpha,7 beta-Di-hydroxyvouacapan-17 beta-oic acid, isolated from P. polygalaeflorus Benth fruits, possesses anti-inflammatory and analgesic properties. In order to gather data for elucidation of the biological mechanism, to improve the anti-inflammatory and analgesic activities and its organic tolerance, hydroxamic acids (IV and VII) and amides (III, V and VI) derivatives were obtained. The IR, H-1 and C-13 NMR and Mass spectrometric data are presented and the synthetic routs discussed(1).

引用

页码：124 / 128

页数：5

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