MOLECULAR-GENETICS OF GLUCAN METABOLISM IN ORAL STREPTOCOCCI

被引：26

作者：

RUSSELL, RRB

机构：

[1] Hunterian Dental Research Unit, London Hospital Medical College, London, E1 2AD England, Turner Street

来源：

ARCHIVES OF ORAL BIOLOGY | 1990年 / 35卷

关键词：

GLUCOSYLTRANSFERASE; BASE SEQUENCE; GLUCAN; STREPTOCOCCUS-MUTANS;

D O I：

10.1016/0003-9969(90)90131-S

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Computer analysis of the primary amino acid sequences deduced from nucleotide sequences of cloned genes from Streptococcus mutans and Strep. downei was used to examine features of enzymes involved in formation and degradation of glucans. All 4 glucosyltransferases for which sequence data are available show a common structure characterized by a series of reiterated repeats in the carboxy-terminal one third of the molecule. These repeats are also found in Strep. mutans glucan-binding protein and resemble those found in enzymes from other bacteria with binding properties.

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页码：S53 / S58

页数：6

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