TRISOMY-4 IN ACUTE NONLYMPHOCYTIC LEUKEMIA - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE

被引：9

作者：

DONTI, E

MACCARI, A

TABILIO, A

ARDISIA, C

CAMPANARI, N

DONTI, GV

机构：

[1] UNIV PERUGIA,DEPT INTERNAL MED 1,I-06100 PERUGIA,ITALY

[2] UNIV PERUGIA,DEPT INTERNAL MED 2,I-06100 PERUGIA,ITALY

[3] UNIV PERUGIA,INST HEMATOL,I-06100 PERUGIA,ITALY

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 60卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90018-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two patients with M2 subtype of acute nonlymphocytic leukemia (ANLL) and trisomy 4 as a primary karyotype change are described. The abnormality was observed in 100% of bone marrow (BM) metaphases in both cases. It appeared alone in one case and was associated with trisomy 13 in 94% of metaphases in the other, These are the second and third cases of ANLL with trisomy 4 documented in Italy. Neither patient appears to have incurred any environmental or therapeutic insult.

引用

页码：195 / 197

页数：3

共 19 条

[1]

ALITALO K, 1985, LANCET, V2, P1035

[2]

Banno S, 1989, Rinsho Ketsueki, V30, P1987

[3]

BRITTON V, 1989, CANCER GENET CYTOGEN, V47, P265

[4] TRISOMY-4 IN A CASE OF ACUTE NONLYMPHOCYTIC LEUKEMIA (M2) [J].