XANTHINE-OXIDASE INHIBITORY ACTIVITY OF SOME PANAMANIAN PLANTS FROM CELASTRACEAE AND LAMIACEAE

被引：28

作者：

GONZALEZ, AG

BAZZOCCHI, IL

MOUJIR, L

RAVELO, AG

CORREA, MD

GUPTA, MP

机构：

[1] UNIV PANAMA,SCH PHARM,PHARMACOGNOST STUDY PANAMANIAN FLORA RES CTR,PANAMA CITY,PANAMA

[2] UNIV PANAMA,HERBARIUM,PANAMA CITY,PANAMA

[3] UNIV LA LAGUNA,DEPT MICROBIOL & BIOL CELULAR,E-38206 TENERIFE,SPAIN

[4] CTR PROD NAT ORGAN ANTONIO GONZALEZ,E-38206 TENERIFE,SPAIN

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1995年 / 46卷 / 01期

关键词：

CELASTRACEAE; LAMIACEAE; XANTHINE OXIDASE; INHIBITOR; BIOASSAY; PANAMA;

D O I：

10.1016/0378-8741(95)01225-3

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Thirty four crude extracts of Panamanian plants, from nine species of Celastraceae and Lamiaceae, were assayed for xanthine oxidase (XO) inhibitory activity. The enzymatic activity was estimated by measuring the increase in absorbance at 290 nm due to uric acid formation. Eighty five percent of the crude extracts were found to possess XO inhibitory activity at 50 mu g/ml and all the extracts of the species from Lamiaceae were active even at 1 mu g/ml. The ethanol extracts of Hyptis obtusiflora Presl ex Benth. (Lamiaceae) and H. lantanaefolia Poit. (Lamiaceae) exhibited the highest activity with an inhibition of approximately 40% at 1 mu g/ml.

引用

页码：25 / 29

页数：5

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