MYOCARDIAL STUNNING AND HIBERNATION - THE PHYSIOLOGY BEHIND THE COLLOQUIALISMS

被引：158

作者：

MARBAN, E

机构：

[1] Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

[2] Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore

来源：

CIRCULATION | 1991年 / 83卷 / 02期

关键词：

D O I：

10.1161/01.CIR.83.2.681

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Stunning and hibernation have become popular terms to describe the disturbances of myocardial function that follow or accompany a reduction in coronary perfusion. This article analyzes the two types of dysfunction from the viewpoint of cellular excitation-contraction coupling. a reduction of cytoplasmic activator calcium can explain hibernation, whereas a lesion in the myofilaments underlies stunning.

引用

收藏

页码：681 / 688

页数：8

相关论文

共 54 条

[1] MYOCARDIAL CONTRACTILE FUNCTION DURING ISCHEMIA AND HYPOXIA [J].

ALLEN, DG ;

ORCHARD, CH .

CIRCULATION RESEARCH, 1987, 60 (02) :153-168

[2] INTRACELLULAR CALCIUM-CONCENTRATION DURING HYPOXIA AND METABOLIC INHIBITION IN MAMMALIAN VENTRICULAR MUSCLE [J].

ALLEN, DG ;

ORCHARD, CH .

JOURNAL OF PHYSIOLOGY-LONDON, 1983, 339 (JUN) :107-122

[3] IMPORTANCE OF PERFUSION PRESSURE IN CORONARY ARTERIES FOR CONTRACTILITY AND OXYGEN CONSUMPTION OF HEART [J].

ARNOLD, G ;

KOSCHE, F ;

MIESSNER, E ;

NEITZERT, A ;

LOCHNER, W .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1968, 299 (04) :339-+

[4] MECHANISM OF MYOCARDIAL STUNNING [J].

BOLLI, R .

CIRCULATION, 1990, 82 (03) :723-738

[5] THE STUNNED MYOCARDIUM - PROLONGED, POST-ISCHEMIC VENTRICULAR DYSFUNCTION [J].

BRAUNWALD, E ;

KLONER, RA .

CIRCULATION, 1982, 66 (06) :1146-1149

[6] REVERSIBLE ISCHEMIC LEFT-VENTRICULAR DYSFUNCTION - EVIDENCE FOR THE HIBERNATING MYOCARDIUM [J].

BRAUNWALD, E ;

RUTHERFORD, JD .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1986, 8 (06) :1467-1470

[7] MYOCARDIAL REPERFUSION - A DOUBLE-EDGED SWORD [J].

BRAUNWALD, E ;

KLONER, RA .

JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (05) :1713-1719

[8] INVIVO ALTERATIONS OF HIGH-ENERGY PHOSPHATES AND INTRACELLULAR PH DURING REVERSIBLE ISCHEMIA IN PIGS - A P-31 MAGNETIC-RESONANCE SPECTROSCOPY STUDY [J].

CAMACHO, SA ;

LANZER, P ;

TOY, BJ ;

GOBER, J ;

VALENZA, M ;

BOTVINICK, EH ;

WEINER, MW .

AMERICAN HEART JOURNAL, 1988, 116 (03) :701-708

[9] MYOCARDIAL HIBERNATION IN THE ISCHEMIC NEONATAL HEART [J].

DOWNING, SE ;

CHEN, V .

CIRCULATION RESEARCH, 1990, 66 (03) :763-772

[10] EFFECTS OF PH ON MYOFILAMENTS AND SARCOPLASMIC-RETICULUM OF SKINNED CELLS FROM CARDIAC AND SKELETAL-MUSCLES [J].

FABIATO, A ;

FABIATO, F .

JOURNAL OF PHYSIOLOGY-LONDON, 1978, 276 (MAR) :233-255

← 1 2 3 4 5 6 →