2 NEOCLERODANE DITERPENOIDS CONTAINING AN UNUSUAL 2,6-DIOXABICYCLO[2.2.1]HEPTANE STRUCTURAL MOIETY

被引：20

作者：

DELATORRE, MC

BRUNO, M

PIOZZI, F

SAVONA, G

OMAR, AA

PERALES, A

RODRIGUEZ, B

机构：

[1] UNIV PALERMO, DIPARTMENTO CHIM ORGAN, ARCHIRAFI 20, I-90123 PALERMO, ITALY

[2] CSIC, INST QUIM ORGAN, E-28006 MADRID, SPAIN

[3] CSIC, INST ROCASOLANO, DEPT RAYOS X, E-28006 MADRID, SPAIN

[4] UNIV ALEXANDRIA, COLL PHARM, ALEXANDRIA, EGYPT

来源：

TETRAHEDRON | 1991年 / 47卷 / 20-21期

关键词：

D O I：

10.1016/S0040-4020(01)86408-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new diterpenoids, teucrolivins G and H, have been isolated from the aerial parts of Teucrium oliverianum (Labiatae). The structures of teucrolivin G [6-alpha,19-diacetoxy-4-alpha,18;15,16-diepoxy-3-oxo-neo-cleroda-13(16), 14-dien-12,8-beta,10-beta-acetal, 1] and teucrolivin H [19-acetoxy-4-alpha,18;15,16-diepoxy-6-alpha-hydroxy-3-oxo-neo-cleroda-13(16),14-dien-12,8-beta,10-beta-acetal, 2] were established mainly by spectroscopic means, including an x-ray diffraction analysis of the former (1). Compounds 1 and 2 possess an unusual 2,6-dioxabicyclo [2.2.1] heptane structural moiety which, to the best of our knowledge, has now been found for the first time in natural products.

引用

页码：3463 / 3470

页数：8

共 26 条

[1]

AJABNOOR M A, 1984, Fitoterapia, V55, P227

[2]

[Anonymous], 1974, INT TABLES XRAY CRYS, VIV

[3] INSECT ANTIFEEDANT ACTIVITY OF CLERODANE DITERPENOIDS AGAINST LARVAE OF SPODOPTERA-LITTORALIS (BOISD) (LEPIDOPTERA) [J].