ROLES OF INTERLEUKIN-1 AND TUMOR-NECROSIS-FACTOR IN LIPOPOLYSACCHARIDE-INDUCED HYPOGLYCEMIA

被引：51

作者：

VOGEL, SN ^{[1
]}

HENRICSON, BE ^{[1
]}

NETA, R ^{[1
]}

机构：

[1] ARMED FORCES RADIOBIOL RES INST,BETHESDA,MD 20814

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 07期

关键词：

D O I：

10.1128/IAI.59.7.2494-2498.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this study, hypoglycemia induced by injection of lipopolysaccharide (LPS) or the recombinant cytokine interleukin-1-alpha or tumor necrosis factor alpha (administered alone or in combination) was compared. LPS-induced hypoglycemia was reversed significantly by recombinant interleukin-1 receptor antagonist.

引用

页码：2494 / 2498

页数：5

共 32 条

[1] BIOLOGY OF MULTIFUNCTIONAL CYTOKINES - IL-6 AND RELATED MOLECULES (IL-1 AND TNF)
AKIRA, S
HIRANO, T
TAGA, T
KISHIMOTO, T
[J]. FASEB JOURNAL, 1990, 4 (11) : 2860 - 2867
[2] BIOLOGICAL PROPERTIES OF RECOMBINANT HUMAN MONOCYTE-DERIVED INTERLEUKIN-1 RECEPTOR ANTAGONIST
AREND, WP
WELGUS, HG
THOMPSON, RC
EISENBERG, SP
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1990, 85 (05) : 1694 - 1697
[3] BAGBY GJ, 1988, CIRC SHOCK, V24, P111
[4] TUMOR-NECROSIS-FACTOR MEDIATES ENDOTOXIC EFFECTS IN MICE
BAUSS, F
DROGE, W
MANNEL, DN
[J]. INFECTION AND IMMUNITY, 1987, 55 (07) : 1622 - 1625
[5] BIRD TA, 1990, J BIOL CHEM, V265, P13578
[6] EVIDENCE FOR DIFFERENT INTERLEUKIN-1 RECEPTORS IN MURINE B-CELL AND T-CELL LINES
BOMSZTYK, K
SIMS, JE
STANTON, TH
SLACK, J
MCMAHAN, CJ
VALENTINE, MA
DOWER, SK
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) : 8034 - 8038
[7] INTERLEUKIN-1 AFFECTS GLUCOSE-HOMEOSTASIS
DELREY, A
BESEDOVSKY, H
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1987, 253 (05): : R794 - R798
[8] ANTIDIABETIC EFFECTS OF INTERLEUKIN-1
DELREY, A
BESEDOVSKY, H
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (15) : 5943 - 5947
[9] TUMOR-NECROSIS-FACTOR (CACHECTIN) IS AN ENDOGENOUS PYROGEN AND INDUCES PRODUCTION OF INTERLEUKIN-1
DINARELLO, CA
CANNON, JG
WOLFF, SM
BERNHEIM, HA
BEUTLER, B
CERAMI, A
FIGARI, IS
PALLADINO, MA
OCONNOR, JV
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1986, 163 (06) : 1433 - 1450
[10] PRIMARY STRUCTURE AND FUNCTIONAL EXPRESSION FROM COMPLEMENTARY-DNA OF A HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST
EISENBERG, SP
EVANS, RJ
AREND, WP
VERDERBER, E
BREWER, MT
HANNUM, CH
THOMPSON, RC
[J]. NATURE, 1990, 343 (6256) : 341 - 346

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