PHENOMENOLOGY AND FUNCTIONING IN 1ST-EPISODE SCHIZOPHRENIA

被引：77

作者：

SHTASEL, DL ^{[1
]}

GUR, RE ^{[1
]}

GALLACHER, F ^{[1
]}

HEIMBERG, C ^{[1
]}

CANNON, T ^{[1
]}

GUR, RC ^{[1
]}

机构：

[1] UNIV PENN, SCH MED, DEPT PSYCHOL, PHILADELPHIA, PA 19104 USA

来源：

SCHIZOPHRENIA BULLETIN | 1992年 / 18卷 / 03期

关键词：

D O I：

10.1093/schbul/18.3.449

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

One current view of schizophrenia is that its dinical and functional features show a deteriorating course, particularly for negative symptoms. However, this is difficult to study in chronic patients who have been exposed to pharmacologic treatment and institutionalization. Examining first-episode (FE) patients can help clarify which symptoms are present initially and how the symptom pattern is linked to functioning. We evaluated a sample of 37 FE patients with schizophrenia and compared them to 70 other schizophrenia (OS) patients on standard clinical scales measures of premorbid functioning, and quality of life. FE patients showed a symptom profile similar to OS patients; in particular, there was no evidence that negative symptoms am less severe in the FE group. Analysis of the clinical data led us to the conclusion that the symptom profile of schizophrenia exists at the outset, that negative symptoms are associated with poor premorbid and current functioning, but that the role of positive symptoms is more complex and may vary in subtypes.

引用

页码：449 / 462

页数：14

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