RECENT ASPECTS OF GLYCOCONJUGATE SYNTHESIS - A SYNTHETIC APPROACH TO THE LINKAGE REGION OF PROTEOGLYCANS

被引：31

作者：

GOTO, F ^{[1
]}

OGAWA, T ^{[1
]}

机构：

[1] UNIV TOKYO,FAC AGR,BUNKYO KU,TOKYO 113,JAPAN

来源：

PURE AND APPLIED CHEMISTRY | 1993年 / 65卷 / 04期

关键词：

D O I：

10.1351/pac199365040793

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A versatile synthetic route to nonsulfated, as well as mono and disulfated glycohexaosyl serines that correspond to the linkage region of proteoglycans is developed by employing a glycotriaosyl donor and a glycotriaosyl acceptor Chemoselective removal of levuloyl groups among other ester groups without causing any acyl migration was carried out and subsequent regiospecific introduction of sulfate groups was achieved successfully.

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页码：793 / 801

页数：9

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