BITTER STEROID GLUCOSIDES, VERNONIOSIDE-A1, VERNONIOSIDE-A2, AND VERNONIOSIDE-A3, AND RELATED VERNONIOSIDE-B1 FROM A POSSIBLE MEDICINAL PLANT, VERNONIA-AMYGDALINA, USED BY WILD CHIMPANZEES

被引：99

作者：

JISAKA, M

OHIGASHI, H

TAKAGAKI, T

NOZAKI, H

TADA, T

HIROTA, M

IRIE, R

HUFFMAN, MA

NISHIDA, T

KAJI, M

KOSHIMIZU, K

机构：

[1] KYOTO UNIV,DEPT FOOD SCI & TECHNOL,KYOTO 606,JAPAN

[2] OKAYAMA UNIV SCI,DEPT CHEM,OKAYAMA 700,JAPAN

[3] SHINSHU UNIV,DEPT BIOSCI & TECHNOL,MATSUMOTO,NAGANO 390,JAPAN

[4] KYOTO UNIV,HUMAN EVOLUT STUDIES LAB,KYOTO 606,JAPAN

[5] UNIV TOKYO,UNIV FOREST CHICHIBU,SAITAMA 368,JAPAN

[6] FUJISAWA PHARMACEUT CO LTD,ANALYT RES LABS,OSAKA 532,JAPAN

来源：

TETRAHEDRON | 1992年 / 48卷 / 04期

关键词：

VERNONIA-AMYGDALINA; BITTER COMPOUND; MEDICINAL PLANT; CHIMPANZEE; VERMONIOSIDE;

D O I：

10.1016/S0040-4020(01)88123-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

From Vernonia amygdalina, a possible medicinal plant used by wild chimpanzees, three bitter steroid glucosides, vernoniosides A1,A2 and A3 and a nonbitter vernonioside B1, were isoluted. The oxygenation patterns of the aglycone parts were new, especially the pattern of the carboxyl group at C21. The oxygen functionalities at C16 were important for the bitter taste.

引用

页码：625 / 632

页数：8

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