TISSUE DISTRIBUTION OF INSULIN-LIKE GROWTH-FACTOR RECEPTORS IN THE TURKEY

被引：21

作者：

MCFARLAND, DC

FERRIN, NH

GILKERSON, KK

PESALL, JE

机构：

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 103卷 / 03期

关键词：

D O I：

10.1016/0305-0491(92)90377-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The distribution and relative insulin-like growth factor (IGF) binding capacities of membranes derived from 14 tissues of the turkey were examined. 2. Affinity cross-linking analyses using [I-125]IGF-I and [I-125]IGF-II with membranes derived from the liver, pectoralis major muscle, gizzard, heart and brain indicated that both IGFs interact with only type-I IGF receptors on these tissues. 3. There was no evidence for the existence of a type-II IGF receptor in any tissue. 4. Although considerable variation was detected in the molecular weights of the IGF receptor alpha subunits between tissues (1 12.2-132.9 kDa), these differences did not appear to influence receptor-ligand affinities.

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页码：601 / 607

页数：7

相关论文

共 36 条

[1] DEVELOPMENTAL EXPRESSION OF RECEPTORS FOR INSULIN, INSULIN-LIKE GROWTH FACTOR-I (IGF-I), AND IGF-II IN RAT SKELETAL-MUSCLE [J].

ALEXANDRIDES, T ;

MOSES, AC ;

SMITH, RJ .

ENDOCRINOLOGY, 1989, 124 (02) :1064-1076

[2] DEVELOPMENTAL REGULATION OF INSULIN AND TYPE-I INSULIN-LIKE GROWTH-FACTOR RECEPTORS AND ABSENCE OF TYPE-II RECEPTORS IN CHICKEN-EMBRYO TISSUES [J].

BASSAS, L ;

LESNIAK, MA ;

SERRANO, J ;

ROTH, J ;

DEPABLO, F .

DIABETES, 1988, 37 (05) :637-644

[3] THE INSULIN-RECEPTORS OF CHICK-EMBRYO SHOW TISSUE-SPECIFIC STRUCTURAL DIFFERENCES WHICH PARALLEL THOSE OF THE INSULIN-LIKE GROWTH FACTOR-I RECEPTORS [J].

BASSAS, L ;

DEPABLO, F ;

LESNIAK, MA ;

ROTH, J .

ENDOCRINOLOGY, 1987, 121 (04) :1468-1476

[4] LOCALIZATION OF BINDING-SITES FOR INSULIN-LIKE GROWTH FACTOR-I (IGF-I) IN THE RAT-BRAIN BY QUANTITATIVE AUTORADIOGRAPHY [J].

BOHANNON, NJ ;

CORP, ES ;

WILCOX, BJ ;

FIGLEWICZ, DP ;

DORSA, DM ;

BASKIN, DG .

BRAIN RESEARCH, 1988, 444 (02) :205-213

[5] CELLULAR-PATTERN OF INSULIN-LIKE GROWTH FACTOR-I (IGF-I) AND TYPE-I IGF RECEPTOR GENE-EXPRESSION IN EARLY ORGANOGENESIS - COMPARISON WITH IGF-II GENE-EXPRESSION [J].

BONDY, CA ;

WERNER, H ;

ROBERTS, CT ;

LEROITH, D .

MOLECULAR ENDOCRINOLOGY, 1990, 4 (09) :1386-1398

[6] MOLECULAR-CLONING OF THE CHICKEN GROWTH-HORMONE RECEPTOR COMPLEMENTARY DEOXYRIBONUCLEIC-ACID - MUTATION OF THE GENE IN SEX-LINKED DWARF CHICKENS [J].

BURNSIDE, J ;

LIOU, SS ;

COGBURN, LA .

ENDOCRINOLOGY, 1991, 128 (06) :3183-3192

[7]

CLAIRMONT KB, 1989, J BIOL CHEM, V264, P16390

[8] INTERACTION OF OVINE SOMATOMEDIN AND MULTIPLICATION STIMULATING ACTIVITY RAT INSULIN-LIKE GROWTH FACTOR-II WITH CULTURED SKELETAL-MUSCLE SATELLITE CELLS [J].

DODSON, MV ;

ALLEN, RE ;

SHIMIZU, N ;

SHIMIZU, Y ;

HOSSNER, KL .

ACTA ENDOCRINOLOGICA, 1987, 116 (03) :425-432

[9] STIMULATION OF DNA-SYNTHESIS IN CHICKEN MUSCLE SATELLITE CELLS BY INSULIN AND INSULIN-LIKE GROWTH-FACTORS - EVIDENCE FOR EXCLUSIVE MEDIATION BY A TYPE-I INSULIN-LIKE GROWTH-FACTOR RECEPTOR [J].

DUCLOS, MJ ;

WILKIE, RS ;

GODDARD, C .

JOURNAL OF ENDOCRINOLOGY, 1991, 128 (01) :35-&

[10] INSULIN-LIKE GROWTH-FACTOR RECEPTORS IN CHICKEN LIVER MEMBRANES - BINDING-PROPERTIES, SPECIFICITY, DEVELOPMENTAL PATTERN AND EVIDENCE FOR A SINGLE RECEPTOR TYPE [J].

DUCLOS, MJ ;

GODDARD, C .

JOURNAL OF ENDOCRINOLOGY, 1990, 125 (02) :199-206

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