HIGHLY EFFICIENT SYNTHESIS OF PROPARGYLTITANIUM AND ALLENYLTITANIUM REAGENTS FROM PROPARGYL HALIDES OR PROPARGYL ALCOHOL DERIVATIVES - PRACTICAL SYNTHESIS OF ALLENYL AND HOMOPROPARGYL ALCOHOLS

被引：94

作者：

NAKAGAWA, T ^{[1
]}

KASATKIN, A ^{[1
]}

SATO, F ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT BIOMOLEC ENGN,MIDORI KU,YOKOHAMA,KANAGAWA 226,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 18期

关键词：

D O I：

10.1016/0040-4039(95)00514-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of Ti(O-i-Pr)(4) / 2 i-PrMgBr, synthetic equivalent of practical Ti(II) reagent, with propargyl halides or propargyl alcohol derivatives affords allenyl titanium compounds in excellent yields, thus providing an efficient and practical method for synthesis of both allenyl and homopropargyl alcohols by the successive treatment with aldehydes or ketones.

引用

页码：3207 / 3210

页数：4

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