6-METHYL-6-AZABICYCLO[3.2.1]OCTAN-3-ALPHA-OL 2,2-DIPHENYLPROPIONATE (AZAPROPHEN), A HIGHLY POTENT ANTIMUSCARINIC AGENT

被引：58

作者：

CARROLL, FI

ABRAHAM, P

PARHAM, K

GRIFFITH, RC

AHMAD, A

RICHARD, MM

PADILLA, FN

WITKIN, JM

CHIANG, PK

机构：

[1] PENWALT CORP,DEPT ORGAN CHEM,DIV PHARMACEUT,ROCHESTER,NY 14603

[2] WALTER REED ARMY INST RES,DEPT APPL BIOCHEM,WASHINGTON,DC 20307

[3] WALTER REED ARMY INST RES,DEPT MED NEUROSCI,WASHINGTON,DC 20307

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 05期

关键词：

D O I：

10.1021/jm00388a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：805 / 809

页数：5

共 19 条

[1]

[Anonymous], 1976, ADV PHYS ORG CHEM

[2]

BEBBINGTON A., 1965, ADVANCE DRUG RES, V2, P143

[3]

CARLTON PL, 1983, PRIMER BEHAVIORAL PH, P15

[4]

CHEUNG YC, 1973, BIOCHEM PHARMACOL, V22, P3099

[5] SYNTHESIS OF N-METHYL-6-AZABICYCLO 3,2,1!OCTAN-3-ONE, AN ALKALOID SUB-UNIT [J].

FURSTOSS, R ;

TEISSIER, P .

JOURNAL OF THE CHEMICAL SOCIETY D-CHEMICAL COMMUNICATIONS, 1970, (06) :384-&

[6] REGULATION OF AMYLASE RELEASE FROM DISPERSED PANCREATIC ACINAR CELLS [J].

GARDNER, JD ;

JACKSON, MJ .

JOURNAL OF PHYSIOLOGY-LONDON, 1977, 270 (02) :439-454

[7]

GORDON RK, 1986, J PHARMACOL EXP THER, V236, P85

[8] ANTI-MUSCARINIC ACTIVITY OF APROPHEN [J].

GORDON, RK ;

PADILLA, FN ;

MOORE, E ;

DOCTOR, BP ;

CHIANG, PK .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (19) :2979-2981

[9]

HUMBLET C, 1981, DRUG DEV RES, V1, P419

[10]

JACKMAN LM, 1969, APPLICATIONS NUCLEAR, P288

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