RADIATION-STERILIZATION OF SEMISYNTHETIC PENICILLINS

被引：13

作者：

JACOBS, GP

机构：

[1] Department of Pharmacy, School of Pharmacy, Hebrew University of Jerusalem, 12065 Jerusalem, P.O.B

来源：

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1979年 / 30卷 / 07期

关键词：

D O I：

10.1016/0020-708X(79)90053-X

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

Gamma-irradiation in the dry state of the semi-synthetic penicillins, amoxycillin trihydrate, flucloxacillin-Na, methicillin-Na results in minimal degradation even following a 5 Mrad dose, suggesting the feasibility of their radiation-sterilization. Carbenicillin-Na is more susceptible to radiation-induced degradation but is nevertheless not affected by 1 Mrad dose. This low" dose may be suitable for carbenicillin with very low initial contamination. © 1979."

引用

页码：417 / 421

页数：5

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[10]

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