STIMULATION OF GLYCOPROTEIN SYNTHESIS BY PHOSPHORYLCHOLINE IN VIVO AND IN LIVER SLICES

被引：13

作者：

MOOKERJEA, S

PARK, CE

CHOW, A

机构：

[1] Banting and Best Department of Medical Research, University of Toronto, Toronto

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 05期

基金：

英国医学研究理事会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-291X(69)90687-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A stimulation of plasma glycoprotein synthesis and a reduction of liver triglycerides in 2-days choline deficient rats were observed within 2 hr of phosphorylcholine administration. Similar treatment with choline had no such effects. The effect of phosphorylcholine, in contrast to choline, was found to be more striking in liver slices on the incorporation of glucosaminel-14C into medium proteins. The effect of phosphorylcholine is dependent on the dose used and the temperature and pH of the medium. © 1969.

引用

页码：851 / +

页数：1