LIQUID-CHROMATOGRAPHIC DETERMINATION OF OXYTETRACYCLINE AND CHLORTETRACYCLINE RESIDUES IN ANIMAL-TISSUES

被引：20

作者：

HORII, S ^{[1
]}

机构：

[1] TOKYO METROPOLITAN RES LAB PUBL HLTH,SHINJUKU KU,TOKYO 169,JAPAN

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1994年 / 17卷 / 01期

关键词：

D O I：

10.1080/10826079408013446

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple and sensitive method has been developed for the simultaneous determination of oxytetracycline and chlortetracycline in animal tissues by liquid chromatography(LC). Tissue samples were extracted with EDTA-McIlvaine buffer(ph4.0)/methanol(3/7). The extracts were purified with Sep-pak C18 and Bond Elut SCX cartridges. Two tetracyclines were separated with a synthetic polymer based-ODS column under basic condition. They were determined by LC with programmable fluorometric detector.

引用

页码：213 / 221

页数：9

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