INHIBITION-MEDIATING DOPAMINE RECEPTORS AND THE CONTROL OF INTRACRANIAL REWARD

被引：3

作者：

KATZ, RJ

机构：

[1] Mental Health Research Institute, Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, 48109, Michigan

来源：

PSYCHOPHARMACOLOGY | 1979年 / 61卷 / 01期

关键词：

Brain stimulation; Dopamine; DPI; ET-495; Intracranial reward; Piribedil;

D O I：

10.1007/BF00426808

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type II receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. Receptor inhibition by piribedil increased responding for reward while receptor activation by 3,4-dihydroxyphenylamino-2-imidazoline reduced responding. Inhibition-mediating receptors may therefore play a role opposite to classic excitation-mediating receptors in controlling reward. © 1979 Springer-Verlag.

引用

页码：39 / 41

页数：3

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